By James A. Hall
Breast melanoma is the most typical malignancy present in ladies. fundamental care companies for girls, together with obstetricians and gynecologists, are usually the 1st to notice abnormalities of their sufferers' well-being and are frequently the resource that their sufferers belief so much in terms of clinical matters. they have to be acquainted with breast care no matter if the sufferer is less than the care of a breast health professional, clinical oncologist, or radiation oncologist. a transparent, concise, state of the art source, An Atlas of Breast ailment presents easy wisdom on anatomy, pathology, and the function of the first care supplier in breast care.
Filled with succinct colour algorithms, charts, graphs, and figures, the Atlas provides complicated details briefly, lucid, and simply comprehensible codecs that may be fast grasped by way of the reader. various tables, illustrative mammograms, and key aspect summaries, drawn from the authors' scientific perform supplement the textual content. colour photomicrographs of pertinent common histology and pathology additionally upload visible impression. those gains and extra make An Atlas of Breast illness a realistic refresher and scientific reference for basic care prone, obstetricians, and gynecologists handling the overall well-being of sufferers with breast ailment.
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Extra resources for An Atlas of Breast Disease (The Encyclopedia of Visual Medicine)
Key Morphological Features of Papillary Carcinoma • Encapsulated mass composed of papillae, tubule cystic structures • Abundant foamy cells in the stroma (Figs. 4) Discussion Typically, papillary carcinoma is composed of one layer of cells arranged in papillae or tubule cystic structures. The cell cytoplasm can be eosinophilic, basophilic, or clear. The same Fuhrman nuclear grading system applies here. 5 The Genitourinary System Fig. 3 Papillary carcinoma with encapsulation (Tumors of the Kidney, Bladder and Related Urinary Structures, Armed Force Institute of Pathology/American Registry of Pathology, 2004 with permission) Renal papillary carcinoma shows differentiation toward both proximal and distal tubules, and it has a more conspicuous stroma than does clear cell carcinoma.
Moreover, the tumor may coexist with epithelial malignancies, and the 48 benign smooth muscle fibers can be mistaken as a sarcomatous component subjecting the patient to unnecessary overtreatment. Immunostainings for HMB 45 and Mart-1 can be helpful in making the distinction. Except for the danger for life-threatening hemorrhages and failure associated with the tumor, angiomyolipoma is generally considered a neoplasm with a benign prognosis. On the other hand, the epithelioid angiomyolipoma variant is now considered malignant.
Importantly there is a grade-dependent decrease in the expression of GAP junction protein connexin 43 [19–21]. This important protein plays an essential role in glial morphology, proliferation, and motility. Underdeveloped cellular processes and cell junctions allow cells to get close (hypercellularity in a fixed bony cavity) and migrate (infiltration of normal tissue). This is in contrast to the hypercellularity in reactive gliosis. In mild to moderate gliosis, the characteristic cellular domain is maintained by the non-overlapping arrangement of the exuberant process arborization [12, 22].
An Atlas of Breast Disease (The Encyclopedia of Visual Medicine) by James A. Hall