Get Acetaminophen - A Medical Dictionary, Bibliography, and PDF

By Icon Health Publications

ISBN-10: 0597843198

ISBN-13: 9780597843198

ISBN-10: 1417512393

ISBN-13: 9781417512393

It is a 3-in-1 reference publication. It provides an entire scientific dictionary protecting enormous quantities of phrases and expressions on the subject of acetaminophen. It additionally offers wide lists of bibliographic citations. eventually, it presents details to clients on tips to replace their wisdom utilizing numerous net assets. The publication is designed for physicians, clinical scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to get to grips with learn devoted to acetaminophen. in case your time is efficacious, this e-book is for you. First, you won't waste time looking out the net whereas lacking loads of appropriate details. moment, the booklet additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing countless numbers of websites.

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Additional info for Acetaminophen - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

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Massive hepatocyte apoptosis and necrosis result in fulminant hepatic failure (FHF). Only 14% of patients diagnosed with FHF recover with medical therapy. Orthotopic liver transplantation (OLT) has dramatically improved the fate of these patients (49% undergo OLT), yet 37% die while awaiting OLT. This gloomy picture is balanced by the unique capacity of the liver to regenerate. Hepatocyte replication leads to a full recovery of liver function and mass 1-2 weeks following surgical, viral or chemical hepatic loss.

5) Activation of opioid receptors in the inner ear will induce similar changes in cellular signaling pathways as activation in the central nervous system. 6) Chronic opiates induce opioid receptor mediated supersensitivity state, characterized by increased activation of adenylate cyclase, cAMPresponse element binding protein (CREB), mitogen- activated kinase (MAP kinase), and Akt (a serine/threonine protein kinase). In order to accomplish these objectives, inner ear tissues will be used for reverse-transcription-polymerase chain reaction (RT-PCR), in situ hybridization, immunohistochernistry, morphological studies, and biochemical assays in both in vitro and in vivo models of acute and chronic opiate use.

However, the mechanism(s) for such resiliency remains unknown. Pilot studies from our laboratory demonstrate that hepatocytes induced to proliferate following the administration of sublethal doses of two model hepatotoxicants (acetaminophen and carbon tetrachloride) have elevated expression of the canalicular ATP-dependent efflux pump for organic anions known as MRP-2, alternatively known as canalicular MRP (cMRP) or c MOAT. We hypothesize that induction of hepatocellular proliferation results in an increased expression of this protein.

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Acetaminophen - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications

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